Duxberry is a small suburb of Sandton and is situated between River Club and Morningside in the North of Johannesburg. Duxberry is security conscious, being surrounded by security booms and closed off roads. Duxberry falls under the jurisdiction of the Sandton Municipality. The River Club Golf Club is just a few blocks away, as is the Sandton Tennis Club. Red Hill is the closest school to Duxberry and the Jules Verne French School is just a couple of blocks away.

Duxberry is situated just five minutes away from the new business centre for Johannesburg, relocated to Sandton. Here can be found Johannesburg's largest and most modern shopping mall, Sandton City, as well as several other malls, making the district a mecca for visitors to the city. This small suburb is serviced by the Morningside shopping centre and is close to the Morningside Clinic and the rehabilitation centre at Tara.